Wasabi vs Horseradish - Differences & Similarities

Cardiovascular System

Section reviewed by cardiologist Astghik Grigoryan

Regular consumption of horseradish, similar to wasabi, could help normalize arterial pressure. Moreover, it may prevent the formation of blood clots (6.7).

In addition, the sulfurous compounds in horseradish can help enhance the elasticity of cerebral and coronary blood vessels, reducing the risk of a heart attack or stroke (6).

According to studies, both wasabi and horseradish may improve lipid profiles, which is important for preventing the development of metabolic syndrome and complications related to it (such as cardiovascular diseases) (8.9.10).

Digestive System

Section reviewed by gastroenterologist Arpi Gasparyan

Horseradish may beneficially affect the digestive system; its laxative effects may reduce symptoms of chronic constipation (11). 

According to animal studies, wasabi may improve the gut microbiome and alleviate inflammatory bowel disease symptoms, mediated through the effect of the compound 6-MSITC (5, 12).

Immune System

6-MSITC, a compound found in wasabi, has anti-inflammatory and anti-microbial effects (13).
ITCs extracted from horseradish had anti-fungal effects against some dermal fungi (14). This means that ITCs may be potentially used to treat some fungal infections (14).

Respiratory System

Horseradish may be used as a potential alternative to pharmaceutical drugs in treating respiratory issues (6). On the other hand, wasabi can stimulate the sinuses. This is great for when you have a stuffy nose!

Food Poisoning

Wasabi, which is often eaten side by side with sushi or sashimi, is believed to provide protection against food poisoning that could result from eating raw fish (15). Wasabi has also been shown to have bactericidal (bacteria-killing) against Staphylococcus aureus and Escherichia coli which are bacteria often involved in food poisoning (16).

Cancer

In wasabi, 6-MSITC has anti-cancer effects (14). 6-MSITC may be a potential compound for controlling cancerous cells (17). Moreover, wasabi has an inhibitory effect against the genotoxicity of acrylamide (18). Acrylamide is usually found in foods that are cooked for a long time or at high temperatures, such as french fries.

Wasabi has also been shown to have an inhibitory effect on stomach carcinogenesis (19).

According to one study, a compound in horseradish called sinigrin causes the death of prostate cancer cells (20).

Thyroid function

Horseradish may interfere with thyroid function. Plants belonging to the Brassicaceae family often have this reputation of disrupting thyroid function when eaten raw or in huge quantities.

Heartburn

Section reviewed by gastroenterologist Arpi Gasparyan

Horseradish and wasabi may cause or worsen heartburn symptoms in people with GERD and peptic ulcer disease; therefore, limiting their consumption in symptomatic people is recommended.

Other Risks

Horseradish is organoleptic and may irritate your senses if it is overly consumed.